ecg analysis module of the labchart pro software version 8 Search Results


labchart version 8  (Data Sciences International)
90
Data Sciences International labchart version 8
Labchart Version 8, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ecg system  (ADInstruments)
95
ADInstruments ecg system
A , <t>Electrocardiographic</t> <t>(ECG)</t> data acquisition in a neonate rat. B , <t>ECG</t> wave signals. C , Tachogram obtained by cardiac interval recording.
Ecg System, supplied by ADInstruments, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ecg analysis module  (ADInstruments)
96
ADInstruments ecg analysis module
a Experimental design of the PLN R14 Δ/Δ intervention study, consisting of ASO#27 treatment with a 4-week loading phase with weekly dosing of 100 mg/kg and a 20-week maintenance phase with dosing of 50 mg/kg once every 4 weeks. Data points for functional and biochemical assessments were obtained at treatment week 4 (T4) which was the primary endpoint, 15 (T15), 19 (T19), and 23 (T23) at the end of the study. b SYBR green qPCR results of cardiac Pln mRNA expression ( n = 3 for wild-type [WT] and n = 4 for PBS and PLN-ASO). c Semi-quantified western blot analysis of PLN protein expression using LV protein lysates. Intensities were normalized to total protein loading control and the PBS treated mice ( n = 3 per group). d Immunofluorescence of WT, PBS treated and PLN-ASO treated PLN R14 Δ/Δ mice after 4 weeks treatment. Sections were co-stained for cardiac Troponin T (green), PLN (red), and DAPI (blue). Note the lower presence of visible PLN aggregations (white arrows) and the higher structural integrity of the PLN-ASO treated hearts vs. PBS control. Stainings were performed in two animals per group. e Representative MRI images after 4 weeks of treatment. f Quantification of LVEF (left ventricular ejection fraction), LVESV (left ventricular end-systolic volume), and LVEDV (left ventricular end-diastolic volume) ( n = 12 for PBS T4, n = 13 for PLN-ASO T4). Wild-type data were previously published, and the average is presented here for reference. g Principle component analysis plot of the first 2 principle components derived from the RNA-sequencing of mice left ventricles. h Representative <t>ECG</t> tracing of mice after 4 weeks of treatment. i Quantification of R, S, and R + S amplitude ( n = 14 for T4) Wild-type data were previously published and the average is presented here for reference. j Representative Masson’s trichrome staining after 4 weeks of treatment of PBS and PLN-ASO treated PLN R14 Δ/Δ cardiac sections. Stainings were performed in four animals per group. k Quantification of myocardial fibrosis based on Masson’s trichrome staining whereby the blue, fibrotic area is presented as the fold change compared to wild-type in percentage of the total tissue slice surface ( n = 4 for all groups). l Kaplan–Meier survival plot of PLN R14 Δ/Δ animals treated with PLN-ASO ( n = 13) and PBS ( n = 14). Three PBS treated animals died during MRI imaging, the other PBS treated animals died at around 8 weeks of age. The “x” marks the 3-time points at which animals were sacrificed for tissue analyses. One-way analysis of variance was used for statistical analyses, with PBS treated animals as the reference group in multiple comparison analyses. Asterix denotes significance level based on two-sided P values compared to PBS with: * P value < 0.05; ** P value < 0.01; *** P value < 0.001; **** P value < 0.0001. Single values are depicted, and error bars represent the standard error of the mean (SEM). ASO antisense oligonucleotide, MRI magnetic resonance imaging, and ECG <t>electrocardiogram.</t> Source data are provided as a .
Ecg Analysis Module, supplied by ADInstruments, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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intellivue m8004a  (Philips Healthcare)
90
Philips Healthcare intellivue m8004a
a Experimental design of the PLN R14 Δ/Δ intervention study, consisting of ASO#27 treatment with a 4-week loading phase with weekly dosing of 100 mg/kg and a 20-week maintenance phase with dosing of 50 mg/kg once every 4 weeks. Data points for functional and biochemical assessments were obtained at treatment week 4 (T4) which was the primary endpoint, 15 (T15), 19 (T19), and 23 (T23) at the end of the study. b SYBR green qPCR results of cardiac Pln mRNA expression ( n = 3 for wild-type [WT] and n = 4 for PBS and PLN-ASO). c Semi-quantified western blot analysis of PLN protein expression using LV protein lysates. Intensities were normalized to total protein loading control and the PBS treated mice ( n = 3 per group). d Immunofluorescence of WT, PBS treated and PLN-ASO treated PLN R14 Δ/Δ mice after 4 weeks treatment. Sections were co-stained for cardiac Troponin T (green), PLN (red), and DAPI (blue). Note the lower presence of visible PLN aggregations (white arrows) and the higher structural integrity of the PLN-ASO treated hearts vs. PBS control. Stainings were performed in two animals per group. e Representative MRI images after 4 weeks of treatment. f Quantification of LVEF (left ventricular ejection fraction), LVESV (left ventricular end-systolic volume), and LVEDV (left ventricular end-diastolic volume) ( n = 12 for PBS T4, n = 13 for PLN-ASO T4). Wild-type data were previously published, and the average is presented here for reference. g Principle component analysis plot of the first 2 principle components derived from the RNA-sequencing of mice left ventricles. h Representative <t>ECG</t> tracing of mice after 4 weeks of treatment. i Quantification of R, S, and R + S amplitude ( n = 14 for T4) Wild-type data were previously published and the average is presented here for reference. j Representative Masson’s trichrome staining after 4 weeks of treatment of PBS and PLN-ASO treated PLN R14 Δ/Δ cardiac sections. Stainings were performed in four animals per group. k Quantification of myocardial fibrosis based on Masson’s trichrome staining whereby the blue, fibrotic area is presented as the fold change compared to wild-type in percentage of the total tissue slice surface ( n = 4 for all groups). l Kaplan–Meier survival plot of PLN R14 Δ/Δ animals treated with PLN-ASO ( n = 13) and PBS ( n = 14). Three PBS treated animals died during MRI imaging, the other PBS treated animals died at around 8 weeks of age. The “x” marks the 3-time points at which animals were sacrificed for tissue analyses. One-way analysis of variance was used for statistical analyses, with PBS treated animals as the reference group in multiple comparison analyses. Asterix denotes significance level based on two-sided P values compared to PBS with: * P value < 0.05; ** P value < 0.01; *** P value < 0.001; **** P value < 0.0001. Single values are depicted, and error bars represent the standard error of the mean (SEM). ASO antisense oligonucleotide, MRI magnetic resonance imaging, and ECG <t>electrocardiogram.</t> Source data are provided as a .
Intellivue M8004a, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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blood pressure module software v1  (ADInstruments)
97
ADInstruments blood pressure module software v1
a Experimental design of the PLN R14 Δ/Δ intervention study, consisting of ASO#27 treatment with a 4-week loading phase with weekly dosing of 100 mg/kg and a 20-week maintenance phase with dosing of 50 mg/kg once every 4 weeks. Data points for functional and biochemical assessments were obtained at treatment week 4 (T4) which was the primary endpoint, 15 (T15), 19 (T19), and 23 (T23) at the end of the study. b SYBR green qPCR results of cardiac Pln mRNA expression ( n = 3 for wild-type [WT] and n = 4 for PBS and PLN-ASO). c Semi-quantified western blot analysis of PLN protein expression using LV protein lysates. Intensities were normalized to total protein loading control and the PBS treated mice ( n = 3 per group). d Immunofluorescence of WT, PBS treated and PLN-ASO treated PLN R14 Δ/Δ mice after 4 weeks treatment. Sections were co-stained for cardiac Troponin T (green), PLN (red), and DAPI (blue). Note the lower presence of visible PLN aggregations (white arrows) and the higher structural integrity of the PLN-ASO treated hearts vs. PBS control. Stainings were performed in two animals per group. e Representative MRI images after 4 weeks of treatment. f Quantification of LVEF (left ventricular ejection fraction), LVESV (left ventricular end-systolic volume), and LVEDV (left ventricular end-diastolic volume) ( n = 12 for PBS T4, n = 13 for PLN-ASO T4). Wild-type data were previously published, and the average is presented here for reference. g Principle component analysis plot of the first 2 principle components derived from the RNA-sequencing of mice left ventricles. h Representative <t>ECG</t> tracing of mice after 4 weeks of treatment. i Quantification of R, S, and R + S amplitude ( n = 14 for T4) Wild-type data were previously published and the average is presented here for reference. j Representative Masson’s trichrome staining after 4 weeks of treatment of PBS and PLN-ASO treated PLN R14 Δ/Δ cardiac sections. Stainings were performed in four animals per group. k Quantification of myocardial fibrosis based on Masson’s trichrome staining whereby the blue, fibrotic area is presented as the fold change compared to wild-type in percentage of the total tissue slice surface ( n = 4 for all groups). l Kaplan–Meier survival plot of PLN R14 Δ/Δ animals treated with PLN-ASO ( n = 13) and PBS ( n = 14). Three PBS treated animals died during MRI imaging, the other PBS treated animals died at around 8 weeks of age. The “x” marks the 3-time points at which animals were sacrificed for tissue analyses. One-way analysis of variance was used for statistical analyses, with PBS treated animals as the reference group in multiple comparison analyses. Asterix denotes significance level based on two-sided P values compared to PBS with: * P value < 0.05; ** P value < 0.01; *** P value < 0.001; **** P value < 0.0001. Single values are depicted, and error bars represent the standard error of the mean (SEM). ASO antisense oligonucleotide, MRI magnetic resonance imaging, and ECG <t>electrocardiogram.</t> Source data are provided as a .
Blood Pressure Module Software V1, supplied by ADInstruments, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 97 stars, based on 1 article reviews
blood pressure module software v1 - by Bioz Stars, 2026-05
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Image Search Results


A , Electrocardiographic (ECG) data acquisition in a neonate rat. B , ECG wave signals. C , Tachogram obtained by cardiac interval recording.

Journal: Brazilian Journal of Medical and Biological Research

Article Title: A method to assess heart rate variability in neonate rats: validation in normotensive and hypertensive animals

doi: 10.1590/1414-431X20209493

Figure Lengend Snippet: A , Electrocardiographic (ECG) data acquisition in a neonate rat. B , ECG wave signals. C , Tachogram obtained by cardiac interval recording.

Article Snippet: RR intervals were recorded over a 30-min period using an ECG system (BioAmp FE231, ADInstruments Ltd.) and LabChart software (version 8, ADInstruments Ltd.).

Techniques:

a Experimental design of the PLN R14 Δ/Δ intervention study, consisting of ASO#27 treatment with a 4-week loading phase with weekly dosing of 100 mg/kg and a 20-week maintenance phase with dosing of 50 mg/kg once every 4 weeks. Data points for functional and biochemical assessments were obtained at treatment week 4 (T4) which was the primary endpoint, 15 (T15), 19 (T19), and 23 (T23) at the end of the study. b SYBR green qPCR results of cardiac Pln mRNA expression ( n = 3 for wild-type [WT] and n = 4 for PBS and PLN-ASO). c Semi-quantified western blot analysis of PLN protein expression using LV protein lysates. Intensities were normalized to total protein loading control and the PBS treated mice ( n = 3 per group). d Immunofluorescence of WT, PBS treated and PLN-ASO treated PLN R14 Δ/Δ mice after 4 weeks treatment. Sections were co-stained for cardiac Troponin T (green), PLN (red), and DAPI (blue). Note the lower presence of visible PLN aggregations (white arrows) and the higher structural integrity of the PLN-ASO treated hearts vs. PBS control. Stainings were performed in two animals per group. e Representative MRI images after 4 weeks of treatment. f Quantification of LVEF (left ventricular ejection fraction), LVESV (left ventricular end-systolic volume), and LVEDV (left ventricular end-diastolic volume) ( n = 12 for PBS T4, n = 13 for PLN-ASO T4). Wild-type data were previously published, and the average is presented here for reference. g Principle component analysis plot of the first 2 principle components derived from the RNA-sequencing of mice left ventricles. h Representative ECG tracing of mice after 4 weeks of treatment. i Quantification of R, S, and R + S amplitude ( n = 14 for T4) Wild-type data were previously published and the average is presented here for reference. j Representative Masson’s trichrome staining after 4 weeks of treatment of PBS and PLN-ASO treated PLN R14 Δ/Δ cardiac sections. Stainings were performed in four animals per group. k Quantification of myocardial fibrosis based on Masson’s trichrome staining whereby the blue, fibrotic area is presented as the fold change compared to wild-type in percentage of the total tissue slice surface ( n = 4 for all groups). l Kaplan–Meier survival plot of PLN R14 Δ/Δ animals treated with PLN-ASO ( n = 13) and PBS ( n = 14). Three PBS treated animals died during MRI imaging, the other PBS treated animals died at around 8 weeks of age. The “x” marks the 3-time points at which animals were sacrificed for tissue analyses. One-way analysis of variance was used for statistical analyses, with PBS treated animals as the reference group in multiple comparison analyses. Asterix denotes significance level based on two-sided P values compared to PBS with: * P value < 0.05; ** P value < 0.01; *** P value < 0.001; **** P value < 0.0001. Single values are depicted, and error bars represent the standard error of the mean (SEM). ASO antisense oligonucleotide, MRI magnetic resonance imaging, and ECG electrocardiogram. Source data are provided as a .

Journal: Nature Communications

Article Title: Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy

doi: 10.1038/s41467-021-25439-0

Figure Lengend Snippet: a Experimental design of the PLN R14 Δ/Δ intervention study, consisting of ASO#27 treatment with a 4-week loading phase with weekly dosing of 100 mg/kg and a 20-week maintenance phase with dosing of 50 mg/kg once every 4 weeks. Data points for functional and biochemical assessments were obtained at treatment week 4 (T4) which was the primary endpoint, 15 (T15), 19 (T19), and 23 (T23) at the end of the study. b SYBR green qPCR results of cardiac Pln mRNA expression ( n = 3 for wild-type [WT] and n = 4 for PBS and PLN-ASO). c Semi-quantified western blot analysis of PLN protein expression using LV protein lysates. Intensities were normalized to total protein loading control and the PBS treated mice ( n = 3 per group). d Immunofluorescence of WT, PBS treated and PLN-ASO treated PLN R14 Δ/Δ mice after 4 weeks treatment. Sections were co-stained for cardiac Troponin T (green), PLN (red), and DAPI (blue). Note the lower presence of visible PLN aggregations (white arrows) and the higher structural integrity of the PLN-ASO treated hearts vs. PBS control. Stainings were performed in two animals per group. e Representative MRI images after 4 weeks of treatment. f Quantification of LVEF (left ventricular ejection fraction), LVESV (left ventricular end-systolic volume), and LVEDV (left ventricular end-diastolic volume) ( n = 12 for PBS T4, n = 13 for PLN-ASO T4). Wild-type data were previously published, and the average is presented here for reference. g Principle component analysis plot of the first 2 principle components derived from the RNA-sequencing of mice left ventricles. h Representative ECG tracing of mice after 4 weeks of treatment. i Quantification of R, S, and R + S amplitude ( n = 14 for T4) Wild-type data were previously published and the average is presented here for reference. j Representative Masson’s trichrome staining after 4 weeks of treatment of PBS and PLN-ASO treated PLN R14 Δ/Δ cardiac sections. Stainings were performed in four animals per group. k Quantification of myocardial fibrosis based on Masson’s trichrome staining whereby the blue, fibrotic area is presented as the fold change compared to wild-type in percentage of the total tissue slice surface ( n = 4 for all groups). l Kaplan–Meier survival plot of PLN R14 Δ/Δ animals treated with PLN-ASO ( n = 13) and PBS ( n = 14). Three PBS treated animals died during MRI imaging, the other PBS treated animals died at around 8 weeks of age. The “x” marks the 3-time points at which animals were sacrificed for tissue analyses. One-way analysis of variance was used for statistical analyses, with PBS treated animals as the reference group in multiple comparison analyses. Asterix denotes significance level based on two-sided P values compared to PBS with: * P value < 0.05; ** P value < 0.01; *** P value < 0.001; **** P value < 0.0001. Single values are depicted, and error bars represent the standard error of the mean (SEM). ASO antisense oligonucleotide, MRI magnetic resonance imaging, and ECG electrocardiogram. Source data are provided as a .

Article Snippet: RR-, PR-, QRS- and QT-intervals, P-duration, P-, Q-, R-, S- and T-amplitudes, ST-height and heart rate were analysed using the ECG Analysis module in the LabChart Pro software version 8 (ADInstruments).

Techniques: Functional Assay, SYBR Green Assay, Expressing, Western Blot, Control, Immunofluorescence, Staining, Derivative Assay, RNA Sequencing, Imaging, Comparison, Magnetic Resonance Imaging